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Novel non-stimulants rescue hyperactive phenotype in an adgrl3.1 mutant zebrafish model of ADHD

ADHD is a highly prevalent neurodevelopmental disorder. The first-line therapeutic for ADHD, methylphenidate, can cause serious side effects including weight loss, insomnia, and hypertension. Therefore, the development of non-stimulant-based therapeutics has been prioritized. However, many of these...

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Detalles Bibliográficos
Autores principales: Sveinsdóttir, Hildur Sóley, Christensen, Christian, Þorsteinsson, Haraldur, Lavalou, Perrine, Parker, Matthew O., Shkumatava, Alena, Norton, William H. J., Andriambeloson, Emile, Wagner, Stéphanie, Karlsson, Karl Ægir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267219/
https://www.ncbi.nlm.nih.gov/pubmed/36400921
http://dx.doi.org/10.1038/s41386-022-01505-z