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Tanshinone IIA promotes vascular normalization and boosts Sorafenib’s anti-hepatoma activity via modulating the PI3K-AKT pathway

Introduction: Angiogenesis is an essential feature of liver cancer. Tumor hypoxia results from abnormal vessel architecture. Numerous studies have sufficiently demonstrated that Tanshinone IIA (Tan IIA) can increase blood flow and enhance microcirculation. The objectives of this study are to: 1 asse...

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Detalles Bibliográficos
Autores principales: Qin, Chengdong, Liu, Siyuan, Zhou, Shiqi, Xia, Xianghou, Hu, Jiejie, Yu, Yang, Ma, Dening
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267387/
https://www.ncbi.nlm.nih.gov/pubmed/37324455
http://dx.doi.org/10.3389/fphar.2023.1189532