Glomerular endothelial glycocalyx-derived heparan sulfate inhibits glomerular leukocyte influx and attenuates experimental glomerulonephritis

Proliferative forms of glomerulonephritis are characterized by the influx of leukocytes, albuminuria, and loss of kidney function. The glomerular endothelial glycocalyx is a thick carbohydrate layer that covers the endothelium and is comprised of heparan sulfate (HS), which plays a pivotal role in g...

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Detalles Bibliográficos
Autores principales: Maciej-Hulme, Marissa L., Van Gemst, Jasper J., Sanderson, Patience, Rops, Angelique L. W. M. M., Berden, Jo H., Smeets, Bart, Amster, I. Jonathan, Rabelink, Ton J., Van Der Vlag, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267401/
https://www.ncbi.nlm.nih.gov/pubmed/37325479
http://dx.doi.org/10.3389/fmolb.2023.1177560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267401/
https://www.ncbi.nlm.nih.gov/pubmed/37325479
http://dx.doi.org/10.3389/fmolb.2023.1177560

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