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Glomerular endothelial glycocalyx-derived heparan sulfate inhibits glomerular leukocyte influx and attenuates experimental glomerulonephritis
Proliferative forms of glomerulonephritis are characterized by the influx of leukocytes, albuminuria, and loss of kidney function. The glomerular endothelial glycocalyx is a thick carbohydrate layer that covers the endothelium and is comprised of heparan sulfate (HS), which plays a pivotal role in g...
Autores principales: | Maciej-Hulme, Marissa L., Van Gemst, Jasper J., Sanderson, Patience, Rops, Angelique L. W. M. M., Berden, Jo H., Smeets, Bart, Amster, I. Jonathan, Rabelink, Ton J., Van Der Vlag, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267401/ https://www.ncbi.nlm.nih.gov/pubmed/37325479 http://dx.doi.org/10.3389/fmolb.2023.1177560 |
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