Effect of Apremilast on LPS-induced immunomodulation and inflammation via activation of Nrf2/HO-1 pathways in rat lungs

Lipopolysaccharides (LPS), the lipid component of gram-negative bacterial cell wall, is recognized as the key factor in acute lung inflammation and is found to exhibit severe immunologic reactions. Phosphodiesterase-4 (PDE-4) inhibitor: “apremilast (AP)” is an immune suppressant and anti-inflammator...

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Detalles Bibliográficos
Autores principales: Al-Harbi, Naif O., Imam, Faisal, Al-Harbi, Mohammad Matar, Qamar, Wajhul, Aljerian, Khaldoon, Khalid Anwer, Md., Alharbi, Mohammed, Almudimeegh, Sultan, Alhamed, Abdullah S., Alshamrani, Ali A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267521/
https://www.ncbi.nlm.nih.gov/pubmed/37323920
http://dx.doi.org/10.1016/j.jsps.2023.05.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267521/
https://www.ncbi.nlm.nih.gov/pubmed/37323920
http://dx.doi.org/10.1016/j.jsps.2023.05.022

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