Development and validation of a UPLC-MS/MS method for simultaneous detection of doxorubicin and sorafenib in plasma: Application to pharmacokinetic studies in rats

An ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) was developed for the simultaneous quantitation of doxorubicin (DOX) and sorafenib (SOR) in rat plasma. Chromatographic separation was performed using a reversed-phase column C(18) (1.7 μm, 1.0 × 100 mm Acquity UPLC BEH...

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Detalles Bibliográficos
Autores principales: Altalal, Alanoud, Almomen, Aliyah, Alkholief, Musaed, Binkhathlan, Ziyad, Alzoman, Nourah Z., Alshamsan, Aws
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267530/
https://www.ncbi.nlm.nih.gov/pubmed/37323919
http://dx.doi.org/10.1016/j.jsps.2023.05.025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267530/
https://www.ncbi.nlm.nih.gov/pubmed/37323919
http://dx.doi.org/10.1016/j.jsps.2023.05.025

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