Reprogramming of Acute Myeloid Leukemia Patients Cells: Harboring Cancer Mutations Requires Targeting of AML Hierarchy

Screening of primary patient acute myeloid leukemia (AML) cells is challenging based on intrinsic characteristics of human AML disease and patient-specific conditions required to sustain AML cells in culture. This is further complicated by inter- and intra-patient heterogeneity, and “contaminating”...

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Detalles Bibliográficos
Autores principales: Golubeva, Diana, Porras, Deanna P, Doyle, Meaghan, Reid, Jennifer C, Tanasijevic, Borko, Boyd, Allison L, Vojnits, Kinga, Elrafie, Amro, Qiao, Amy, Bhatia, Mickie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Cell-Based Drug Development, Screening, and Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267577/
https://www.ncbi.nlm.nih.gov/pubmed/37226319
http://dx.doi.org/10.1093/stcltm/szad022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267577/
https://www.ncbi.nlm.nih.gov/pubmed/37226319
http://dx.doi.org/10.1093/stcltm/szad022

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