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Metformin Improves Functional Outcomes, Activates Neural Precursor Cells, and Modulates Microglia in a Sex-Dependent Manner After Spinal Cord Injury

Spinal cord injury (SCI) results in devastating patient outcomes with few treatment options. A promising approach to improve outcomes following SCI involves the activation of endogenous precursor populations including neural stem and progenitor cells (NSPCs) which are located in the periventricular...

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Detalles Bibliográficos
Autores principales: Gilbert, Emily A B, Livingston, Jessica, Garcia-Flores, Emilio, Kehtari, Tarlan, Morshead, Cindi M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267579/
https://www.ncbi.nlm.nih.gov/pubmed/37209417
http://dx.doi.org/10.1093/stcltm/szad030