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Structural basis of ELKS/Rab6B interaction and its role in vesicle capturing enhanced by liquid-liquid phase separation

ELKS proteins play a key role in organizing intracellular vesicle trafficking and targeting in both neurons and non-neuronal cells. While it is known that ELKS interacts with the vesicular traffic regulator, the Rab6 GTPase, the molecular basis governing ELKS-mediated trafficking of Rab6-coated vesi...

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Detalles Bibliográficos
Autores principales: Jin, Gaowei, Lin, Leishu, Li, Kaiyue, Li, Jiashan, Yu, Cong, Wei, Zhiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267580/
https://www.ncbi.nlm.nih.gov/pubmed/37172719
http://dx.doi.org/10.1016/j.jbc.2023.104808