Propensity of Patient-Derived iPSCs for Retinal Differentiation: Implications for Autologous Cell Replacement

Prior to use, newly generated induced pluripotent stem cells (iPSC) should be thoroughly validated. While excellent validation and release testing assays designed to evaluate potency, genetic integrity, and sterility exist, they do not have the ability to predict cell type-specific differentiation c...

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Detalles Bibliográficos
Autores principales: Cooke, Jessica A, Voigt, Andrew P, Collingwood, Michael A, Stone, Nicholas E, Whitmore, S Scott, DeLuca, Adam P, Burnight, Erin R, Anfinson, Kristin R, Vakulskas, Christopher A, Reutzel, Austin J, Daggett, Heather T, Andorf, Jeaneen L, Stone, Edwin M, Mullins, Robert F, Tucker, Budd A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Enabling Technologies for Cell-Based Clinical Translations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267581/
https://www.ncbi.nlm.nih.gov/pubmed/37221451
http://dx.doi.org/10.1093/stcltm/szad028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267581/
https://www.ncbi.nlm.nih.gov/pubmed/37221451
http://dx.doi.org/10.1093/stcltm/szad028

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