Recurrent infection transiently expands human tissue T cells while maintaining long-term homeostasis

Chronic viral infections are known to lead to T cell exhaustion or dysfunction. However, it remains unclear if antigen exposure episodes from periodic viral reactivation, such as herpes simplex virus type-2 (HSV-2) recrudescence, are sufficient to induce T cell dysfunction, particularly in the conte...

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Detalles Bibliográficos
Autores principales: Davé, Veronica, Richert-Spuhler, Laura E., Arkatkar, Tanvi, Warrier, Lakshmi, Pholsena, Thepthara, Johnston, Christine, Schiffer, Joshua T., Prlic, Martin, Lund, Jennifer M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267593/
https://www.ncbi.nlm.nih.gov/pubmed/37314481
http://dx.doi.org/10.1084/jem.20210692

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267593/
https://www.ncbi.nlm.nih.gov/pubmed/37314481
http://dx.doi.org/10.1084/jem.20210692

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