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Recurrent infection transiently expands human tissue T cells while maintaining long-term homeostasis
Chronic viral infections are known to lead to T cell exhaustion or dysfunction. However, it remains unclear if antigen exposure episodes from periodic viral reactivation, such as herpes simplex virus type-2 (HSV-2) recrudescence, are sufficient to induce T cell dysfunction, particularly in the conte...
Autores principales: | Davé, Veronica, Richert-Spuhler, Laura E., Arkatkar, Tanvi, Warrier, Lakshmi, Pholsena, Thepthara, Johnston, Christine, Schiffer, Joshua T., Prlic, Martin, Lund, Jennifer M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267593/ https://www.ncbi.nlm.nih.gov/pubmed/37314481 http://dx.doi.org/10.1084/jem.20210692 |
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