eIF3 mRNA selectivity profiling reveals eIF3k as a cancer‐relevant regulator of ribosome content

eIF3, whose subunits are frequently overexpressed in cancer, regulates mRNA translation from initiation to termination, but mRNA‐selective functions of individual subunits remain poorly defined. Using multiomic profiling upon acute depletion of eIF3 subunits, we observed that while eIF3a, b, e, and...

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Detalles Bibliográficos
Autores principales: Duan, Haoran, Zhang, Siqiong, Zarai, Yoram, Öllinger, Rupert, Wu, Yanmeng, Sun, Li, Hu, Cheng, He, Yaohui, Tian, Guiyou, Rad, Roland, Kong, Xiangquan, Cheng, Yabin, Tuller, Tamir, Wolf, Dieter A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267700/
https://www.ncbi.nlm.nih.gov/pubmed/37155573
http://dx.doi.org/10.15252/embj.2022112362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267700/
https://www.ncbi.nlm.nih.gov/pubmed/37155573
http://dx.doi.org/10.15252/embj.2022112362

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