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Nicotinamide riboside functions during development while beta-hydroxybutyrate functions during adulthood to extend C. elegans lifespan
Nicotinamide riboside (NR), a form of vitamin B3 and a nicotinamide adenine dinucleotide (NAD (+) ) precursor, has been shown to activate the mitochondrial unfolded protein response (UPR (mt) ) and extend the lifespan when supplemented to C. elegans. The ketone body and histone deacetylase (HDAC) in...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Caltech Library
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267727/ https://www.ncbi.nlm.nih.gov/pubmed/37325193 http://dx.doi.org/10.17912/micropub.biology.000841 |