Cargando…
Acute osimertinib exposure induces electrocardiac changes by synchronously inhibiting the currents of cardiac ion channels
Introduction: As the third generation of epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), osimertinib has demonstrated more significant cardiotoxicity than previous generations of EGFR-TKIs. Investigating the mechanism of osimertinib cardiotoxicity can provide a reference for a...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267729/ https://www.ncbi.nlm.nih.gov/pubmed/37324483 http://dx.doi.org/10.3389/fphar.2023.1177003 |