Involvement of CD40-CD40L and ICOS-ICOSL in the development of chronic rhinosinusitis by targeting eosinophils

BACKGROUND: Chronic rhinosinusitis (CRS), whose prevalence and pathogenesis are age-related, is characterized by nasal tissue eosinophil infiltration. CD40-CD40 ligand (CD40L) pathway involves in the eosinophil-mediated inflammation, and inducible co-stimulator (ICOS)–ICOS ligand (ICOSL) signal can...

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Detalles Bibliográficos
Autores principales: Zhou, Aina, Shi, Chenxi, Fan, Yuhui, Zheng, Yushuang, Wang, Jue, Liu, Zhichen, Xie, Huanxia, Liu, Jisheng, Jiao, Qingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267736/
https://www.ncbi.nlm.nih.gov/pubmed/37325657
http://dx.doi.org/10.3389/fimmu.2023.1171308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267736/
https://www.ncbi.nlm.nih.gov/pubmed/37325657
http://dx.doi.org/10.3389/fimmu.2023.1171308

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