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Perlecan: a review of its role in neurologic and musculoskeletal disease

Perlecan is a 500 kDa proteoglycan residing in the extracellular matrix of endothelial basement membranes with five distinct protein domains and three heparan sulfate chains. The complex structure of perlecan and the interaction it has with its local environment accounts for its various cellular and...

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Detalles Bibliográficos
Autores principales: Lavorgna, Tessa R., Gressett, Timothy E., Chastain, Wesley H., Bix, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267744/
https://www.ncbi.nlm.nih.gov/pubmed/37324385
http://dx.doi.org/10.3389/fphys.2023.1189731