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Oxidative Release of O-Glycans under Neutral Conditions for Analysis of Glycoconjugates Having Base-Sensitive Substituents

[Image: see text] Protein O-glycosylation is one of the most diverse post-translational modifications. A critical step in the analysis of O-glycomes is the release of glycans from glycoconjugates. Current release methods rely mainly on β-elimination, which can result in peeling reactions and loss of...

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Detalles Bibliográficos
Autores principales: Vos, Gaël M., Weber, Julia, Sweet, Igor R., Hooijschuur, Kevin C., Sastre Toraño, Javier, Boons, Geert-Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267892/
https://www.ncbi.nlm.nih.gov/pubmed/37259796
http://dx.doi.org/10.1021/acs.analchem.3c00127