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Loss of LRP1 in Adult Neural Stem Cells Impairs Migration to Ischemic Lesions

After ischemia, cells in the brain parenchyma upregulate stromal derived factor 1 (SDF1), driving chemokine receptor CXCR4-mediated migration of adult neural stem cells to the ischemic injury. We discovered a novel regulator of CXCR4 in neural stem cells, low-density lipoprotein receptor related pro...

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Detalles Bibliográficos
Autores principales: Dietert, Kristi, Mahesula, Swetha, Hegde, Sheetal, Verschelde, John, Reed, Pamela, Sprague, Shane, Kokovay, Erzsebet, Sayre, Naomi L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267954/
https://www.ncbi.nlm.nih.gov/pubmed/37186298
http://dx.doi.org/10.1093/stmcls/sxad034