Tonic activation of GABA(B) receptors via GAT-3 mediated GABA release reduces network activity in the developing somatosensory cortex in GAD67-GFP mice

The efficiency of neocortical information processing critically depends on the balance between the glutamatergic (excitatory, E) and GABAergic (inhibitory, I) synaptic transmission. A transient imbalance of the E/I-ratio during early development might lead to neuropsychiatric disorders later in life...

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Detalles Bibliográficos
Autores principales: Ueberbach, Timo, Simacek, Clara A., Tegeder, Irmgard, Kirischuk, Sergei, Mittmann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267986/
https://www.ncbi.nlm.nih.gov/pubmed/37325697
http://dx.doi.org/10.3389/fnsyn.2023.1198159

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10267986/
https://www.ncbi.nlm.nih.gov/pubmed/37325697
http://dx.doi.org/10.3389/fnsyn.2023.1198159

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