Synthetic and Medicinal Chemistry Approaches Toward WEE1 Kinase Inhibitors and Its Degraders

[Image: see text] WEE1 is a checkpoint kinase critical for mitotic events, especially in cell maturation and DNA repair. Most cancer cells’ progression and survival are linked with elevated levels of WEE1 kinase. Thus, WEE1 kinase has become a new promising druggable target. A few classes of WEE1 in...

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Detalles Bibliográficos
Autores principales: Alli, Vidya Jyothi, Yadav, Pawan, Suresh, Vavilapalli, Jadav, Surender Singh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268025/
https://www.ncbi.nlm.nih.gov/pubmed/37323408
http://dx.doi.org/10.1021/acsomega.3c01558

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268025/
https://www.ncbi.nlm.nih.gov/pubmed/37323408
http://dx.doi.org/10.1021/acsomega.3c01558

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