Heterogeneous expression of alternatively spliced lncRNA mediates vascular smooth cell plasticity

9p21.3 locus polymorphisms have the strongest correlation with coronary artery disease, but as a noncoding locus, disease connection is enigmatic. The lncRNA ANRIL found in 9p21.3 may regulate vascular smooth muscle cell (VSMC) phenotype to contribute to disease risk. We observed significant heterog...

Descripción completa

Detalles Bibliográficos
Autores principales: Mayner, Jaimie M., Masutani, Evan M., Demeester, Elena, Kumar, Aditya, Macapugay, Gail, Beri, Pranjali, Lo Sardo, Valentina, Engler, Adam J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Physical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268236/
https://www.ncbi.nlm.nih.gov/pubmed/37276403
http://dx.doi.org/10.1073/pnas.2217122120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268236/
https://www.ncbi.nlm.nih.gov/pubmed/37276403
http://dx.doi.org/10.1073/pnas.2217122120

Ejemplares similares