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CARD9 attenuates Aβ pathology and modifies microglial responses in an Alzheimer’s disease mouse model

Recent advances have highlighted the importance of several innate immune receptors expressed by microglia in Alzheimer’s disease (AD). In particular, mounting evidence from AD patients and experimental models indicates pivotal roles for TREM2, CD33, and CD22 in neurodegenerative disease progression....

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Detalles Bibliográficos
Autores principales: Ennerfelt, Hannah, Holliday, Coco, Shapiro, Daniel A., Zengeler, Kristine E., Bolte, Ashley C., Ulland, Tyler K., Lukens, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268238/
https://www.ncbi.nlm.nih.gov/pubmed/37276426
http://dx.doi.org/10.1073/pnas.2303760120