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The Drosophila chemokine–like Orion bridges phosphatidylserine and Draper in phagocytosis of neurons
Phagocytic clearance of degenerating neurons is triggered by “eat-me” signals exposed on the neuronal surface. The conserved neuronal eat-me signal phosphatidylserine (PS) and the engulfment receptor Draper (Drpr) mediate phagocytosis of degenerating neurons in Drosophila. However, how PS is recogni...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268242/ https://www.ncbi.nlm.nih.gov/pubmed/37276397 http://dx.doi.org/10.1073/pnas.2303392120 |