NgR1 binding to reovirus reveals an unusual bivalent interaction and a new viral attachment protein

Nogo-66 receptor 1 (NgR1) binds a variety of structurally dissimilar ligands in the adult central nervous system to inhibit axon extension. Disruption of ligand binding to NgR1 and subsequent signaling can improve neuron outgrowth, making NgR1 an important therapeutic target for diverse neurological...

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Detalles Bibliográficos
Autores principales: Sutherland, Danica M., Strebl, Michael, Koehler, Melanie, Welsh, Olivia L., Yu, Xinzhe, Hu, Liya, dos Santos Natividade, Rita, Knowlton, Jonathan J., Taylor, Gwen M., Moreno, Rodolfo A., Wörz, Patrick, Lonergan, Zachery R., Aravamudhan, Pavithra, Guzman-Cardozo, Camila, Kour, Sukhleen, Pandey, Udai Bhan, Alsteens, David, Wang, Zhao, Prasad, B. V. Venkataram, Stehle, Thilo, Dermody, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268256/
https://www.ncbi.nlm.nih.gov/pubmed/37276413
http://dx.doi.org/10.1073/pnas.2219404120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268256/
https://www.ncbi.nlm.nih.gov/pubmed/37276413
http://dx.doi.org/10.1073/pnas.2219404120

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