C-4-Modified Isotetrones Prevent Biofilm Growth and Persister Cell Resuscitation in Mycobacterium smegmatis

[Image: see text] Hyperphosphorylated nucleotide (p)ppGpp, synthesized by Rel protein, regulates the stringent response pathway responsible for biofilm and persister cell growth in mycobacteria. The discovery of vitamin C as an inhibitor of Rel protein activities raises the prospect of tetrone lacto...

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Detalles Bibliográficos
Autores principales: Bag, Kingshuk, Pal, Aditya Kumar, Basu, Subhadip, Singla, Mamta, Sarkar, Biplab, Chatterji, Dipankar, Maiti, Prabal Kumar, Ghosh, Anirban, Jayaraman, Narayanaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268289/
https://www.ncbi.nlm.nih.gov/pubmed/37323400
http://dx.doi.org/10.1021/acsomega.3c00822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268289/
https://www.ncbi.nlm.nih.gov/pubmed/37323400
http://dx.doi.org/10.1021/acsomega.3c00822

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