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A Liquid Chromatography High-Resolution Tandem Mass Spectrometry Method to Quantify QS-21 Adjuvant and Its Degradation Products in Liposomal Drug Formulations

[Image: see text] Identification and quantification of an active adjuvant and its degradation product/s in drug formulations are important to ensure drug product safety and efficacy. QS-21 is a potent adjuvant that is currently involved in several clinical vaccine trials and a constituent of license...

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Detalles Bibliográficos
Autores principales: Abucayon, Erwin G., Barrientos, Rodell C., Torres, Oscar B., Sweeney, Scott, Whalen, Connor, Matyas, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268291/
https://www.ncbi.nlm.nih.gov/pubmed/37323401
http://dx.doi.org/10.1021/acsomega.3c01877