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A Liquid Chromatography High-Resolution Tandem Mass Spectrometry Method to Quantify QS-21 Adjuvant and Its Degradation Products in Liposomal Drug Formulations
[Image: see text] Identification and quantification of an active adjuvant and its degradation product/s in drug formulations are important to ensure drug product safety and efficacy. QS-21 is a potent adjuvant that is currently involved in several clinical vaccine trials and a constituent of license...
Autores principales: | Abucayon, Erwin G., Barrientos, Rodell C., Torres, Oscar B., Sweeney, Scott, Whalen, Connor, Matyas, Gary R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268291/ https://www.ncbi.nlm.nih.gov/pubmed/37323401 http://dx.doi.org/10.1021/acsomega.3c01877 |
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