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Chondroitin 4-O-sulfation regulates hippocampal perineuronal nets and social memory

Glycan alterations are associated with aging, neuropsychiatric, and neurodegenerative diseases, although the contributions of specific glycan structures to emotion and cognitive functions remain largely unknown. Here, we used a combination of chemistry and neurobiology to show that 4-O-sulfated chon...

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Detalles Bibliográficos
Autores principales: Huang, Huiqian, Joffrin, Amélie M., Zhao, Yuan, Miller, Gregory M., Zhang, Grace C., Oka, Yuki, Hsieh-Wilson, Linda C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268298/
https://www.ncbi.nlm.nih.gov/pubmed/37279269
http://dx.doi.org/10.1073/pnas.2301312120