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Odd–even disparity in the population of slipped hairpins in RNA repeat sequences with implications for phase separation

Low-complexity nucleotide repeat sequences, which are implicated in several neurological disorders, undergo liquid–liquid phase separation (LLPS) provided the number of repeat units, n, exceeds a critical value. Here, we establish a link between the folding landscapes of the monomers of trinucleotid...

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Detalles Bibliográficos
Autores principales: Maity, Hiranmay, Nguyen, Hung T., Hori, Naoto, Thirumalai, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268303/
https://www.ncbi.nlm.nih.gov/pubmed/37276412
http://dx.doi.org/10.1073/pnas.2301409120