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Optogenetic stimulation of basal forebrain cholinergic neurons prevents neuroinflammation and neuropsychiatric manifestations in pristane induced lupus mice

BACKGROUND: Neuroinflammation has been identified as one of the primary pathogenic factors of neuropsychiatric systemic lupus erythematosus (NPSLE). However, there are no dedicated treatments available in clinics to alleviate neuroinflammation in NPSLE. It has been proposed that stimulating basal fo...

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Detalles Bibliográficos
Autores principales: Yun, Yang, Wang, Xuejiao, Xu, Jingyi, Chen, Jingyu, Wang, Xueru, Yang, Pingting, Qin, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268425/
https://www.ncbi.nlm.nih.gov/pubmed/37322485
http://dx.doi.org/10.1186/s12993-023-00213-y