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Combination effects of amino acid transporter LAT1 inhibitor nanvuranlat and cytotoxic anticancer drug gemcitabine on pancreatic and biliary tract cancer cells

BACKGROUND: Cytotoxic anticancer drugs widely used in cancer chemotherapy have some limitations, such as the development of side effects and drug resistance. Furthermore, monotherapy is often less effective against heterogeneous cancer tissues. Combination therapies of cytotoxic anticancer drugs wit...

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Detalles Bibliográficos
Autores principales: Nishikubo, Kou, Ohgaki, Ryuichi, Liu, Xingming, Okanishi, Hiroki, Xu, Minhui, Endou, Hitoshi, Kanai, Yoshikatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268460/
https://www.ncbi.nlm.nih.gov/pubmed/37322479
http://dx.doi.org/10.1186/s12935-023-02957-z