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Cartilage regeneration and inflammation modulation in knee osteoarthritis following injection of allogeneic adipose-derived mesenchymal stromal cells: a phase II, triple-blinded, placebo controlled, randomized trial

BACKGROUND: Intra-articular injection of mesenchymal stromal cells (MSCs) with immunomodulatory features and their paracrine secretion of regenerative factors proposed a noninvasive therapeutic modality for cartilage regeneration in knee osteoarthritis (KOA). METHODS: Total number of 40 patients wit...

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Detalles Bibliográficos
Autores principales: Sadri, Bahareh, Hassanzadeh, Mohammad, Bagherifard, Abolfazl, Mohammadi, Javad, Alikhani, Mehdi, Moeinabadi-Bidgoli, Kasra, Madani, Hoda, Diaz-Solano, Dylana, Karimi, Shahedeh, Mehrazmay, Mohammad, Mohammadpour, Mehdi, Vosough, Massoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268462/
https://www.ncbi.nlm.nih.gov/pubmed/37316949
http://dx.doi.org/10.1186/s13287-023-03359-8