Dihydropyrazole Derivatives Act as Potent α-Amylase Inhibitors and Free Radical Scavengers: Synthesis, Bioactivity Evaluation, Structure–Activity Relationship, ADMET, and Molecular Docking Studies

[Image: see text] Dihydropyrazole (1–22) derivatives were synthesized from already synthesized chalcones. The structures of all of the synthesized compounds were confirmed by elemental analysis and various spectroscopic techniques. Furthermore, the synthesized compounds were screened against α amyla...

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Detalles Bibliográficos
Autores principales: Ali, Arif, Shah, Muhammad Ishaq Ali, Fu, Chaoping, Hussain, Zubair, Qureshi, Muhammad Nasimullah, Farman, Saira, Parveen, Zahida, Zada, Amir, Nayab, Saira, Fazil, Perveen, Ateeq, Muhammad, Rehman, Gauhar, Naeem, Mohammad, Ibrahim, Mohammad, Khan, Momin, Khan, Waliullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268634/
https://www.ncbi.nlm.nih.gov/pubmed/37332823
http://dx.doi.org/10.1021/acsomega.3c00529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268634/
https://www.ncbi.nlm.nih.gov/pubmed/37332823
http://dx.doi.org/10.1021/acsomega.3c00529

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