Removal of AMR plasmids using a mobile, broad host-range CRISPR-Cas9 delivery tool

Antimicrobial resistance (AMR) genes are widely disseminated on plasmids. Therefore, interventions aimed at blocking plasmid uptake and transfer may curb the spread of AMR. Previous studies have used CRISPR-Cas-based technology to remove plasmids encoding AMR genes from target bacteria, using either...

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Detalles Bibliográficos
Autores principales: Walker-Sünderhauf, David, Klümper, Uli, Pursey, Elizabeth, Westra, Edze R., Gaze, William H., van Houte, Stineke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2023
Materias:
Antimicrobials and AMR
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268836/
https://www.ncbi.nlm.nih.gov/pubmed/37226834
http://dx.doi.org/10.1099/mic.0.001334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10268836/
https://www.ncbi.nlm.nih.gov/pubmed/37226834
http://dx.doi.org/10.1099/mic.0.001334

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