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The role of TMS 12 in the staphylococcal multidrug efflux protein QacA

OBJECTIVES: To elucidate the importance of a region in QacA predicted to be important in antimicrobial substrate recognition. METHODS: A total of 38 amino acid residues within or flanking putative transmembrane helix segment (TMS) 12 of QacA were individually replaced with cysteine using site-direct...

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Detalles Bibliográficos
Autores principales: Dashtbani-Roozbehani, Abolfazl, Chitsaz, Mohsen, Brown, Melissa H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269129/
https://www.ncbi.nlm.nih.gov/pubmed/37100459
http://dx.doi.org/10.1093/jac/dkad121