Population Pharmacokinetic Analyses for Tebipenem after Oral Administration of Pro-Drug Tebipenem Pivoxil Hydrobromide

Tebipenem pivoxil hydrobromide (TBP-PI-HBr) is an oral (PO) carbapenem pro-drug that is converted to the active moiety tebipenem in the enterocytes. Tebipenem has activity against multidrug-resistant Gram-negative pathogens, including extended-spectrum beta lactamase-producing Enterobacterales, and...

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Detalles Bibliográficos
Autores principales: Ganesan, H., Gupta, V. K., Safir, M. C., Bhavnani, S. M., Talley, A. K., Melnick, D., Rubino, C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269146/
https://www.ncbi.nlm.nih.gov/pubmed/37191505
http://dx.doi.org/10.1128/aac.01451-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269146/
https://www.ncbi.nlm.nih.gov/pubmed/37191505
http://dx.doi.org/10.1128/aac.01451-22

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