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Parameterization of the miniPEG-Modified γPNA Backbone: Toward Induced γPNA Duplex Dissociation
[Image: see text] γ-Modified peptide nucleic acids (γPNAs) serve as potential therapeutic agents against genetic diseases. Miniature poly(ethylene glycol) (miniPEG) has been reported to increase solubility and binding affinity toward genetic targets, yet details of γPNA structure and dynamics are no...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269335/ https://www.ncbi.nlm.nih.gov/pubmed/37195939 http://dx.doi.org/10.1021/acs.jctc.2c01163 |