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Circulating neutrophils activated by cancer cells and M2 macrophages promote gastric cancer progression during PD-1 antibody-based immunotherapy

Aims: To analyze the correlation between the neutrophil-to-lymphocyte ratio (NLR) and prognosis of advanced gastric cancer (AGC) patients treated by PD-1 antibody-based therapy and to delineate molecular characteristics of circulating neutrophils by single-cell RNA sequencing (scRNA-seq). Methods: T...

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Detalles Bibliográficos
Autores principales: Zhou, Chenfei, Guo, Liting, Cai, Qu, Xi, Wenqi, Yuan, Fei, Zhang, Huan, Yan, Chao, Huang, Lei, Zhu, Zhenggang, Zhang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269372/
https://www.ncbi.nlm.nih.gov/pubmed/37333017
http://dx.doi.org/10.3389/fmolb.2023.1081762