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Oxygen concentration modulates colibactin production

Up to 25% of the E. coli strains isolated from the feces of healthy humans harbor the pks genomic island encoding the synthesis of colibactin, a genotoxic metabolite. Evidence is accumulating for an etiologic role of colibactin in colorectal cancer. Little is known about the conditions of expression...

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Detalles Bibliográficos
Autores principales: Bossuet, Nadège, Guyonnet, Cécile, Chagneau, Camille V, Tang-Fichaux, Min, Penary, Marie, Loubet, Dorian, Branchu, Priscilla, Oswald, Eric, Nougayrede, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269391/
https://www.ncbi.nlm.nih.gov/pubmed/37312436
http://dx.doi.org/10.1080/19490976.2023.2222437