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Systemic exposure to bacterial amyloid curli alters the gut mucosal immune response and the microbiome, exacerbating Salmonella-induced arthritis

The Salmonella biofilm-associated amyloid protein, curli, is a dominant instigator of systemic inflammation and autoimmune responses following Salmonella infection. Systemic curli injections or infection of mice with Salmonella Typhimurium induce the major features of reactive arthritis, an autoimmu...

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Detalles Bibliográficos
Autores principales: Bessho, Shingo, Grando, Kaitlyn C. M., Kyrylchuk, Kathrine, Miller, Amanda, Klein-Szanto, Andres J., Zhu, Wenhan, Gallucci, Stefania, Tam, Vincent, Tükel, Çagla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269392/
https://www.ncbi.nlm.nih.gov/pubmed/37317012
http://dx.doi.org/10.1080/19490976.2023.2221813