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Systemic exposure to bacterial amyloid curli alters the gut mucosal immune response and the microbiome, exacerbating Salmonella-induced arthritis
The Salmonella biofilm-associated amyloid protein, curli, is a dominant instigator of systemic inflammation and autoimmune responses following Salmonella infection. Systemic curli injections or infection of mice with Salmonella Typhimurium induce the major features of reactive arthritis, an autoimmu...
Autores principales: | Bessho, Shingo, Grando, Kaitlyn C. M., Kyrylchuk, Kathrine, Miller, Amanda, Klein-Szanto, Andres J., Zhu, Wenhan, Gallucci, Stefania, Tam, Vincent, Tükel, Çagla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269392/ https://www.ncbi.nlm.nih.gov/pubmed/37317012 http://dx.doi.org/10.1080/19490976.2023.2221813 |
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