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Alteration of adeS Contributes to Tigecycline Resistance and Collateral Sensitivity to Sulbactam in Acinetobacter baumannii

The treatment of extensively drug-resistant (XDR) A. baumannii has emerged as a major problem. Tigecycline (TGC) and sulbactam (SUL) are both effective antibiotics against XDR A. baumannii. Here, we investigated the in-host evolution and mechanism of collateral sensitivity (CS) phenomenon in develop...

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Detalles Bibliográficos
Autores principales: Yang, Yunxing, Liu, Xiaochen, Zhou, Danyan, He, Jintao, Chen, Qiong, Xu, Qingye, Wu, Shenghai, Zhang, Weiying, Yao, Yue, Fu, Ying, Hua, Xiaoting, Yu, Yunsong, Wang, Xianjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269438/
https://www.ncbi.nlm.nih.gov/pubmed/37184390
http://dx.doi.org/10.1128/spectrum.04594-22