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Two-Component Response Regulator OmpR Regulates Mucoviscosity through Energy Metabolism in Klebsiella pneumoniae

Hypermucoviscosity is a hallmark of hypervirulent Klebsiella pneumoniae (hvKP). However, the molecular basis of its regulation is largely unknown. We hypothesize that hypermucoviscosity is modulated via two-component signal transduction systems (TCSs). In-frame deletion mutants of all 33 response re...

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Detalles Bibliográficos
Autores principales: Wang, Lijun, Huang, Xueting, Jin, Qian, Tang, Jie, Zhang, Hua, Zhang, Jing-Ren, Wu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269446/
https://www.ncbi.nlm.nih.gov/pubmed/37097167
http://dx.doi.org/10.1128/spectrum.00544-23