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Baicalein Suppresses NLRP3 and AIM2 Inflammasome-Mediated Pyroptosis in Macrophages Infected by Mycobacterium tuberculosis via Induced Autophagy

Mycobacterium tuberculosis (Mtb) continues to pose a significant threat to global health because it causes granulomas and systemic inflammatory responses during active tuberculosis (TB). Mtb can induce macrophage pyroptosis, which results in the release of IL-1β and causes tissue damage, thereby pro...

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Detalles Bibliográficos
Autores principales: Ning, Bangzuo, Shen, Jingjing, Liu, Fanglin, Zhang, Hemin, Jiang, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269511/
https://www.ncbi.nlm.nih.gov/pubmed/37125940
http://dx.doi.org/10.1128/spectrum.04711-22