NH125 Sensitizes Staphylococcus aureus to Cell Wall-Targeting Antibiotics through the Inhibition of the VraS Sensor Histidine Kinase

Staphylococcus aureus utilizes the two-component regulatory system VraSR to receive and relay environmental stress signals, and it is implicated in the development of bacterial resistance to several antibiotics through the upregulation of cell wall synthesis. VraS inhibition was shown to extend or r...

Descripción completa

Detalles Bibliográficos
Autores principales: Bhattarai, Shrijan, Marsh, Lane, Knight, Kelsey, Ali, Liaqat, Gomez, Antonio, Sunderhaus, Allison, Abdel Aziz, May H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269531/
https://www.ncbi.nlm.nih.gov/pubmed/37227302
http://dx.doi.org/10.1128/spectrum.04861-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269531/
https://www.ncbi.nlm.nih.gov/pubmed/37227302
http://dx.doi.org/10.1128/spectrum.04861-22

Ejemplares similares