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Identification of Fungus-Derived Natural Products as New Antigiardial Scaffolds

There is an unmet need for effective therapies for treating diseases associated with the intestinal parasite Giardia lamblia. In this study, a library of chemically validated purified natural products and fungal extracts was screened for chemical scaffolds that can inhibit the growth of G. lamblia....

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Detalles Bibliográficos
Autores principales: Hulverson, Matthew A., Michaels, Samantha A., Lee, Jin Woo, Wendt, Karen L., Tran, Linh T., Choi, Ryan, Van Voorhis, Wesley C., Cichewicz, Robert H., Ojo, Kayode K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269678/
https://www.ncbi.nlm.nih.gov/pubmed/37039683
http://dx.doi.org/10.1128/spectrum.00647-23