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Protein Disulfide Isomerase and Extracellular Adherence Protein Cooperatively Potentiate Staphylococcal Invasion into Endothelial Cells

Invasion of host cells is an important feature of Staphylococcus aureus. The main internalization pathway involves binding of the bacteria to host cells, e.g., endothelial cells, via a fibronectin (Fn) bridge between S. aureus Fn binding proteins and α(5)β(1)-integrin, followed by phagocytosis. The...

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Detalles Bibliográficos
Autores principales: Leidecker, Marleen, Bertling, Anne, Hussain, Muzaffar, Bischoff, Markus, Eble, Johannes A., Fender, Anke C., Jurk, Kerstin, Rumpf, Christine, Herrmann, Mathias, Kehrel, Beate E., Niemann, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269700/
https://www.ncbi.nlm.nih.gov/pubmed/36995240
http://dx.doi.org/10.1128/spectrum.03886-22