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PP2Acα-B′/PR61 Holoenzyme of Toxoplasma gondii Is Required for the Amylopectin Metabolism and Proliferation of Tachyzoites

Here, we report that the inhibition of the PP2A subfamily by okadaic acid results in an accumulation of polysaccharides in the acute infection stage (tachyzoites) of Toxoplasma gondii, which is a protozoan of global zoonotic importance and a model for the apicomplexan parasites. The loss of the cata...

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Detalles Bibliográficos
Autores principales: Zhao, Mingxiu, Yang, Yi, Shi, Yue, Chen, Xueqiu, Yang, Yimin, Pan, Lingtao, Du, Zhendong, Sun, Hongchao, Yao, Chaoqun, Ma, Guangxu, Du, Aifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269777/
https://www.ncbi.nlm.nih.gov/pubmed/37199633
http://dx.doi.org/10.1128/spectrum.00104-23