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SARS-CoV-2 Inhibits NRF2-Mediated Antioxidant Responses in Airway Epithelial Cells and in the Lung of a Murine Model of Infection
Several viruses have been shown to modulate the transcription factor nuclear factor erythroid 2-related factor 2 (NRF2), the master regulator of redox homeostasis. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for the COVID-19 pandemic, also seems to disrupt the balan...
Autores principales: | Qu, Yue, Haas de Mello, Aline, Morris, Dorothea R., Jones-Hall, Yava L., Ivanciuc, Teodora, Sattler, Rachel A., Paessler, Slobodan, Menachery, Vineet D., Garofalo, Roberto P., Casola, Antonella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10269779/ https://www.ncbi.nlm.nih.gov/pubmed/37022178 http://dx.doi.org/10.1128/spectrum.00378-23 |
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